Ebiosciences 61-3351-82 Anti-Mouse Cd335 (Nkp46) Pe-Efluor 610, 100 Ug

Ebiosciences 61-3351-82 Anti-Mouse Cd335 (Nkp46) Pe-Efluor 610, 100 Ug

  • The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known as CD335
  • CD335, a member of the natural cytotoxicity receptor (NCR) family, is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail
  • Expression of CD335 is uniquely found on NK cells (including immature NK cells, defined as DX5- CD3-, and thereby allowing discrimination between NKT cells and NK cells
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The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known as CD335.CD335, a member of the natural cytotoxicity receptor (NCR) family, is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail. Expression of CD335 is uniquely found on NK cells (including immature NK cells, defined as DX5- CD3-, and thereby allowing discrimination between NKT cells and NK cells (NKp46plus, CD3-).Furthermore, unlike many of the NK markers which also stain NKT cells, staining with 29A1.4 is not strain specific. Staining has been shown on C57Bl/6, SJL, CBA/CA and BALB/C strains.NKp46 has been shown to play a role in NK cell-mediated lysis of several tumor cells and pathogen-infected cell lines. The 29A1.4 monoclonal antibody has been shown to activate NK cells in vitro .The 29A1.4 monoclonal antibody does not deplete NK cells in vivo .

  • The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known as CD335
  • CD335, a member of the natural cytotoxicity receptor (NCR) family, is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail
  • Expression of CD335 is uniquely found on NK cells (including immature NK cells, defined as DX5- CD3-, and thereby allowing discrimination between NKT cells and NK cells
Binding

Misc.

Brand

eBiosciences

Label

eBioScience

Manufacturer

eBioScience

Model

61-3351-82

MPN

61-3351-82

PartNumber

61-3351-82

ProductGroup

BISS

ProductTypeName

LAB_SUPPLY

Publisher

eBioScience

Studio

eBioScience

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